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High Cholesterol Treatment in Mumbai

Lowering Your Cholesterol - and Your Lifetime Cardiovascular Risk - Through Targeted Care

High cholesterol is one of the most prevalent and most preventable risk factors for heart attack and stroke - and one of the most undertreated because it causes no symptoms until the damage is already done. High cholesterol treatment in Mumbai at Shree Hospitals provides comprehensive lipid management and cholesterol reduction for cardiovascular risk through expert physician assessment, accurate cardiovascular risk stratification, and individually selected statin and non-statin therapy for hypercholesterolaemia. Our approach combines evidence-based pharmacological therapy with structured dietary and lifestyle modification - achieving meaningful LDL cholesterol reduction that demonstrably reduces the risk of heart attack, stroke, and cardiovascular death over the long term.

What is High Cholesterol Treatment?

Hypercholesterolaemia - elevated blood cholesterol - accelerates the deposition of cholesterol-rich plaques within the walls of coronary, cerebral, and peripheral arteries - a process called atherosclerosis that narrowed these arteries progressively over decades before causing heart attack, stroke, or limb ischaemia. Because this process is entirely silent until a plaque ruptures or causes critical narrowing, most people with high cholesterol are unaware of the damage occurring until a cardiovascular event forces the discovery.

Lipid management and cholesterol reduction for cardiovascular risk at Shree Hospitals begins with a fasting lipid profile - measuring total cholesterol, LDL, HDL, and triglycerides - followed by comprehensive cardiovascular risk calculation using validated scoring tools that integrate cholesterol levels with age, sex, blood pressure, diabetes, smoking status, and family history. LDL cholesterol targets are then set based on the patient's calculated risk category - below 1.4 mmol/L for patients with established cardiovascular disease, below 1.8 mmol/L for very high-risk patients, and below 2.6 mmol/L for high-risk patients.

 
Statin and non-statin therapy for hypercholesterolaemia uses high-intensity statins as first-line therapy - atorvastatin 40 to 80mg or rosuvastatin 20 to 40mg - achieving 40 to 55% LDL reduction. For patients not reaching target on maximum statin therapy, ezetimibe is added for a further 15 to 20% reduction. For very high-risk patients with familial hypercholesterolaemia or established cardiovascular disease not at LDL target, PCSK9 inhibitor injections provide the most powerful LDL reduction available - achieving reductions of 50 to 60% beyond statin therapy.

When Should Cholesterol Be Checked and Treated?

• All adults above 40 years - or earlier with family history of premature cardiovascular disease
• Anyone with established cardiovascular disease, diabetes, or chronic kidney disease
• Patients with familial hypercholesterolaemia - autosomal dominant inherited severe hypercholesterolaemia
• Patients with xanthelasma, tendon xanthomata, or corneal arcus below 45 years
• Annual monitoring for anyone already on lipid-lowering therapy until stable at target

How is Cardiovascular Risk Assessed?

• Fasting lipid profile - total cholesterol, LDL, HDL, triglycerides, and non-HDL cholesterol
• Ten-year cardiovascular risk calculation using validated risk calculator
• Family history of premature coronary disease before 55 years in men or 65 years in women
• Carotid intima-media thickness or coronary artery calcium score for risk reclassification in intermediate-risk patients
• LDL cholesterol reduction targets are based on the calculated risk category - not on cholesterol level alone

24×7 Emergency Care

Our Approach to High Cholesterol Treatment

At Shree Hospitals, high cholesterol treatment in Mumbai is delivered through a structured cardiovascular risk reduction programme - combining accurate risk stratification, evidence-based pharmacological therapy, dietary counselling, and regular lipid monitoring. Our physicians do not treat a cholesterol number in isolation - they treat the patient's overall cardiovascular risk with the most appropriate and effective combination of interventions.

High-Intensity Statin Therapy

Every patient with elevated cholesterol undergoes formal cardiovascular risk assessment - integrating lipid levels, blood pressure, diabetes status, smoking, age, sex, and family history using validated risk calculators. Risk category determines LDL target - and therefore treatment intensity. Patients with established cardiovascular disease are automatically classified as very high risk regardless of baseline cholesterol level.

Root Cause Investigation

First-line pharmacological treatment for most patients with elevated LDL and moderate to very high cardiovascular risk is high-intensity statin therapy - atorvastatin 40 to 80mg or rosuvastatin 20 to 40mg - providing 40 to 55% LDL reduction. Statin therapy is initiated at the recommended dose and safety monitoring including liver enzymes and creatine kinase is performed at 8 to 12 weeks after initiation.

Combination Therapy for LDL Target Achievement

Patients not reaching their LDL target on maximum statin therapy receive add-on ezetimibe - further reducing LDL by 15 to 20%. Patients with familial hypercholesterolaemia or established cardiovascular disease still not at target on combined therapy are assessed for PCSK9 inhibitor injection therapy - providing the most powerful LDL cholesterol reduction available in current clinical practice.

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